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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T64147 | ERK1/2 inhibitor 6 | ||
ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. ERK1/2 inhibitor 6 has shown potential for the study or prevention of cancer, inflammation or other proliferative diseases. | |||
T79047 | MEK-IN-6 | ERK | |
MEK-IN-6 (Example 69), a potent MEK inhibitor, effectively inhibits ERK1/2 (Thr202/Tyr204) phosphorylation in A375 cells, with an IC50 of 2 nM, making it valuable for cancer research [1]. | |||
T63229 | ITK inhibitor 6 | ||
ITK inhibitor 6 is a selective and potent ITK inhibitor that acts on ITK (IC50: 4 nM), BTK (IC50: 133 nM), JAK3 (IC50: 320 nM), EGFR (IC50: 2360 nM), LCK (IC50: 155 nM). ITK inhibitor 6 inhibited the phosphorylation of P... | |||
T36676 | Rineterkib hydrochloride | ||
Rineterkib hydrochloride (compound B) is an orally active RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly relat... | |||
T36717 | RWJ-56110 dihydrochloride | ||
RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits... |